Immunoinformatics driven construction of multi-epitope vaccine candidate against Ascaris lumbricoides using its entire immunogenic epitopes.
Rimanpreet KaurNaina AroraSuraj Singh RawatAnand Kumar KeshriNeha SinghSumit Kumar ShowPramod KumarAmit MishraAmit PrasadPublished in: Expert review of vaccines (2021)
We identified highly antigenic peptides of Ascaris from its proteome with good potential to induce innate as well as humoral immune response. These peptides were used to design a chimeric vaccine against Ascariasis infection, which can be used for prophylactic purpose but needs experimental and clinical validation.