Cost-effectiveness of five prenatal screening strategies for trisomies and other unbalanced chromosomal abnormalities: model-based analysis.

Alicia le BrasL J SalomonL BussièresV MalanC ElieH MahallatiYves VilleM VekemansI Durand-Zaleski

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2020)

Extending cfDNA to lower risk thresholds or even to all pregnancies would detect more trisomies, but at greater expense and with lower detection rate of other UBCA, compared with the historical strategy. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

pregnant women
preterm birth
copy number
real time pcr
label free
dna methylation
pregnancy outcomes