EGR1 Is Implicated in Right Ventricular Cardiac Remodeling Associated with Pulmonary Hypertension.
Maria LaggnerFelicitas OberndorferBahar GolabiJonas BauerAndreas ZuckermannPhilipp HackerIrene M LangNika Skoro-SajerChristian GergesShahrokh TaghaviPeter JakschMichael MildnerHendrik Jan AnkersmitBernhard MoserPublished in: Biology (2022)
Our findings improved our understanding of the molecular events driving reverse cardiac remodeling following surgery. EGR1 might represent a promising candidate for targeted therapy of PH patients not eligible for surgical treatment.