High iron-mediated increased oral fungal burden, oral-to-gut transmission, and changes to pathogenicity of Candida albicans in oropharyngeal candidiasis.
Aparna TripathiAnubhav NaharRishabh SharmaTrevor KanaskieNezar Al-HebshiSumant PuriPublished in: Journal of oral microbiology (2022)
Host iron can potentially alter infection severity and dissemination, efficacy of antifungal treatment, and host immune response during OPC. Clinical isolates showed most of these effects of iron, despite exhibiting a varied cell wall composition-change response to iron.