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Dissecting the Mechanisms of Intestinal Immune Homeostasis by Analyzing T-Cell Immune Response in Crohn's Disease and Colorectal Cancer.

Tianming JiangJie ZhengNana LiXiaodong LiJixing HeJunde ZhouBoshi SunQiang Chi
Published in: Current gene therapy (2024)
Finally, the analysis of regulon networks revealed several promising candidates for cell-specific transcription factors (TFs). This study focused on the immune molecular mechanism under intestinal diseases. It contributed to the novel insight of depicting a detailed immune landscape and revealing T-cell responding mechanisms in CD and CRC.
Keyphrases
  • single cell
  • immune response
  • transcription factor
  • mesenchymal stem cells