State of the Art in Combination Immuno/Radiotherapy for Brain Metastases: Systematic Review and Meta-Analysis.

Masoumeh NajafiAmin JahanbakhshiMarzieh GomarCinzia IottiLucia GiaccheriniOmid RezaieFrancesco CavallieriLetizia DeantonioLilia BardosciaAndrea BottiAngela SardaroSalvatore CozziPatrizia Ciammella

Published in: Current oncology (Toronto, Ont.) (2022)

A combination of immuno/radiotherapy (IR) for the treatment of patients with BMs from melanoma and non-small-cell lung carcinoma has prolonged overall survival and reduced mortality rate, with acceptable toxicity. In terms of timing, RT seems to have the best effect on the result when performed before or simultaneously with immunotherapy.

Keyphrases

brain metastases
early stage
small cell lung cancer
locally advanced
radiation therapy
radiation induced
single cell
oxidative stress
cardiovascular events
squamous cell carcinoma
type diabetes
rectal cancer
skin cancer