Gut Microbiome and Osteoarthritis: Insights From the Naturally Occurring Canine Model of Osteoarthritis.
Christina StevensSamantha NorrisLiubov ArbeevaScott CarterMasataka EnomotoAmanda E NelsonBenedict Duncan X LascellesPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
Similar to recent studies in humans, the present study did not demonstrate a significant difference in the fecal microbial communities between dogs with OA pain and healthy control dogs. Future research in this naturally occurring model should expand on these data and relate the gut microbiome to gut permeability and circulating proinflammatory and anti-inflammatory molecules to better understand the influence of the gut microbiome on OA and OA pain.