High titers of both rheumatoid factor and anti-CCP antibodies at baseline in patients with rheumatoid arthritis are associated with increased circulating baseline TNF level, low drug levels, and reduced clinical responses: a post hoc analysis of the RISING study.
Tsutomu TakeuchiNobuyuki MiyasakaTakashi InuiToshiro YanoToru YoshinariTohru AbeTakao KoikePublished in: Arthritis research & therapy (2017)
ClinicalTrials.gov, NCT00691028 . Retrospectively registered on 3 June 2008.