Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer.
Julia DubowitzAlexandra I ZieglerRichard BeareFabian Jost-BrinkmannAdam K WalkerRyan D GillisAeson ChangNi-Chun ChungOlga A MartinFrédéric HollandeBernhard RiedelErica K SloanPublished in: PloS one (2023)
These preclinical studies found no evidence that choice of anesthetic agent used during cancer resection surgery affected either short-term perioperative events or long-term cancer outcomes in mouse models of breast cancer. These findings raise the possibility that mouse models do not recapitulate perioperative events in cancer patients. Nonetheless, the findings suggest that future evaluation of effects of anesthesia on cancer outcomes should focus on cancer types other than breast cancer.