De novo synthesis of dimerization-ready flavan unit via intramolecular Pummerer/Friedel-Crafts cascade.

Vipul V BetkekarKeisuke Suzuki Ken Ohmori

Published in: Organic & biomolecular chemistry (2022)

We describe the de novo synthesis of a dimerization-ready flavan derivative via the Pummerer/Friedel-Crafts cascade. This method allowed facile access to oligomeric proanthocyanidin natural products. The total synthesis of procyanidin B4 was achieved by this strategy.

Keyphrases

quantum dots
reduced graphene oxide
gold nanoparticles
energy transfer
metal organic framework