CCR2 Genetic Polymorphism And Its Potential Effect On HIV Acquisition In A Population Of Children Living In The Northern Region Of Cameroon.
Marie Nicole NgoufackCéline Nguefeu NkenfouBarbara Atogho TiedeuLinda Chapdeleine Mekue MouafoBeatrice DambayaElvis Ndukong NdziCharles KouanfackGeorges Nguefack-TsagueWilfred Fon MbachamAlexis NdjoloPublished in: The application of clinical genetics (2019)
The CCR2-64I allele is relatively common in the Northern Region of Cameroon, with a similar distribution among HIV-exposed un-infected and infected children. As this allele alone does not seem to confer protection against HIV-1 infection, further studies using genotype-combination of CCR2 polymorphism and other single nucleotide polymorphisms would be of great relevance in both HIV prevention and novel therapeutic strategies.