lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.

Hang LiuZiyang SunGang LuoYuehao HuHongjiang RuanBing TuJuehong LiCunyi Fan

Published in: Stem cell reviews and reports (2023)

Our study demonstrated that the lncRNA MEG3 promoted osteogenic differentiation of TDSCs and thus the formation of heterotopic ossification, which could be a potential therapeutic target.

Keyphrases

stem cells
long non coding rna
long noncoding rna
cell proliferation
high glucose
epithelial mesenchymal transition
diabetic rats
resting state
oxidative stress
cell therapy
climate change
mesenchymal stem cells