Effect of tumor burden and radical surgery on survival difference between upfront, early interval or delayed cytoreductive surgery in ovarian cancer.
Martina Aida AngelesBastien CabarrouAntonio Gil-MorenoMaria-Assumpció Pérez-BenaventeEmanuela SpagnoloAgnieszka RychlikCarlos Martinez GomezFrédéric GuyonIgnacio Zapardiel GutiérrezDenis QuerleuClaire IllacFederico E Migliorelli FalconeSarah BétrianGwénaël FerronAlicia Hernández GutiérrezAlejandra MartinezPublished in: Journal of gynecologic oncology (2021)
The benefit of complete PDS compared with NACT was maximal in patients with a low complexity score. In patients with low tumor burden, there was a survival benefit of PDS over early IDS or DDS. In women with high tumor load, DDS impaired the oncological outcome.