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The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings.

Rupesh V AgrawalIlaria TestiSarakshi MahajanYew Sen YuenAniruddha Kishandutt AgarwalAndres RousselotDhananjay RajeDinesh Visva GunasekeranOnn Min KonTalin Barisani-AsenbauerJohn H KempenAmod GuptaDouglas A JabsJustine R SmithBahram BodaghiManfred ZierhutMarc DeSmetPeter Mc CluskeyMamta AgarwalManisha AgarwalKanika AggarwalMukesh AgrawalHassan Al-DhibiSofia AndroudiFatma AsyariManohar Babu BalasundaramKalpana Babu MurthyEdoardo BaglivoAlay BankerReema BansalSoumyava BasuDigamber BeheraJyotirmay BiswasEster CarreñoLaure CaspersSoon Phaik CheeRomi ChhabraCimino LucaLuz Elena Concha Del RioEmmett T CunninghamAndrè Luiz Land CuriDipankar DasEkaterina DenisovaAlastair Keith DennistonMarie-Hélène ErreraAlejandro FonollosaAmala GeorgeDebra A GoldsteinYan Guex CrosierAvinash GurbaxaniAlessandro InvernizziHazlita M IsaShah Md IslamNicholas JonesDeeksha KatochMoncef KhairallahAmit KhoslaMichal KramerAmitabh KumarAtul KumarRina La Distia NoraRichard LeeCareen LowderSaurabh LuthraPadmamalini MahendradasDorine MakhoulShahana MazumdarSalil MehtaElisabetta MiserocchiManabu MochizukiOli S MohamedCristina MuccioliMarion R MunkSomasheila MurthyShishir NarainHeloísa Moraes Do NascimentoPiergiorgio NeriMyhanh NguyenAnnabelle A OkadaPinar OzdalAlan PalestineFrancesco PichiS R RathinamAriel SchlaenShobha SehgalH Nida SenAman SharmaKusum SharmaSamir S ShoughyNirbhai SinghRamandeep SinghMasoud SoheilianSudharshan SridharanJennifer E ThorneChristoph TappeinerStephen TeohMaria Sofia TognonIlknur Tugal-TutkunMudit TyagiHarvey UyDaniel Vitor Vasconcelos SantosNatasa Vidovic ValentincicMark WestcottRyoji YanaiBety Yanez AlvarezRahman ZahedurQuan Dong NguyenCarlos PavesioVishali Gupta
Published in: Ocular immunology and inflammation (2020)
An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interactive online questionnaires, guided by background knowledge from published literature, 486 consensus statements for initiating ATT were generated and deliberated amongst 81 global uveitis experts. The median score of five was considered reaching consensus for initiating ATT. The median score of four was tabled for deliberation through Delphi round 2 in a face-to-face meeting. This report describes the methodology adopted and followed through the consensus process, which help elucidate the guidelines for initiating ATT in patients with choroidal TB.
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