Immune cytopenias as a continuum in inborn errors of immunity: An in-depth clinical and immunological exploration.

Daniele ZamaFrancesca ContiMattia MorattiMaria E CantariniElena FacchiniBeatrice RivaltaRoberto RondelliArcangelo PreteSimona FerrariMarco SeriAndrea Pession

Published in: Immunity, inflammation and disease (2021)

The synergy between hematologists and immunologists can improve and fasten diagnosis and management of patients with immune cytopenias through a wide focused clinical/immunophenotypical characterization, which identifies children worthy of IEI-related molecular analysis, favouring a genetic IEI diagnosis and potentially unveiling new targeted-gene variants responsible for IEI phenotype.

Keyphrases

genome wide
copy number
young adults
emergency department
patient safety
dna methylation
gene expression
drug delivery
cancer therapy
transcription factor
electronic health record