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Stress Drivers of Glucose Dynamics during Ozone Exposure Measured Using Radiotelemetry in Rats.

Andres R HenriquezSamantha J SnowThomas W JacksonJohn S HouseAlison A Motsinger-ReifCavin K Ward-CavinessMette C SchladweilerDevin I AlewelColette N MillerAimen K FarrajMehdi S HazariRachel GrindstaffDavid Diaz-SanchezAndrew J GhioUrmila P Kodavanti
Published in: Environmental health perspectives (2022)
We demonstrated the temporality of neuroendocrine-stress-mediated biological sequalae responsible for ozone-induced glucose metabolic dysfunction and mechanism in a rodent model. Stress hormones assessment with real-time glucose monitoring may be useful in identifying interactions among irritant pollutants and stress-related illnesses. https://doi.org/10.1289/EHP11088.
Keyphrases
  • stress induced
  • hydrogen peroxide
  • type diabetes
  • blood glucose
  • metabolic syndrome
  • high glucose
  • heat stress
  • nitric oxide
  • blood pressure
  • insulin resistance
  • endothelial cells