Login / Signup

Hepatoprotective properties of Penthorum chinense Pursh against carbon tetrachloride-induced acute liver injury in mice.

Meng WangXiao-Jiao ZhangRuibing FengYun JiangDa-Yong ZhangChengwei HePeng LiJian-Bo Wan
Published in: Chinese medicine (2017)
Results indicated that the pretreatment of PCP (10.3 g/kg BW) effectively protected against CCl4-induced acute liver injury, which was comparable to efficacy of silymarin (100 mg/kg). This hepatoprotective effects might be attributed to amelioration of CCl4-induced oxidative stress via activating Nrf2 signaling pathway.
Keyphrases
  • liver injury
  • drug induced
  • signaling pathway
  • pi k akt
  • oxidative stress
  • epithelial mesenchymal transition
  • hydrogen peroxide
  • induced apoptosis
  • high fat diet induced
  • type diabetes
  • metabolic syndrome
  • wild type