Hepatoprotective properties of Penthorum chinense Pursh against carbon tetrachloride-induced acute liver injury in mice.
Meng WangXiao-Jiao ZhangRuibing FengYun JiangDa-Yong ZhangChengwei HePeng LiJian-Bo WanPublished in: Chinese medicine (2017)
Results indicated that the pretreatment of PCP (10.3 g/kg BW) effectively protected against CCl4-induced acute liver injury, which was comparable to efficacy of silymarin (100 mg/kg). This hepatoprotective effects might be attributed to amelioration of CCl4-induced oxidative stress via activating Nrf2 signaling pathway.