The shift in tuberculosis timing among people living with HIV in the course of antiretroviral therapy scale-up in Malawi.
Hannock M TweyaCaryl FeldackerJames MpungaHenry KanyerereTom HellerPrakash GaneshDave NkosiMike KaluluGeorge SinkalaThomas SatumbaSam PhiriPublished in: Journal of the International AIDS Society (2020)
The decline in TB incidence over calendar years suggests protective effects of early ART initiation. The high TB incidence within the first month of ART highlights the need for more sensitive tools such as X-ray and GeneXpert to identify patients living with HIV who have clinical and subclinical TB disease at ART initiation.
Keyphrases
- antiretroviral therapy
- mycobacterium tuberculosis
- hiv infected
- hiv aids
- human immunodeficiency virus
- end stage renal disease
- hiv infected patients
- risk factors
- hiv positive
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- high resolution
- magnetic resonance
- patient reported outcomes
- south africa
- hepatitis c virus
- adverse drug