Correlates of circulating osteoprotegerin in women with a pathogenic or likely pathogenic variant in the BRCA1 gene.

Sarah S Park Tasnim Zaman Shana J Kim Jennifer D Brooks Andy Kin On Wong Jan A Lubiński Steven A Narod Leonardo Salmena Joanne Kotsopoulos

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)

These findings suggest that circulating OPG levels are not impacted by non-genetic factors in high-risk women.

Keyphrases

genome wide
copy number
breast cancer risk
polycystic ovary syndrome
pregnancy outcomes
type diabetes
gene expression
adipose tissue
immune response