Retinoic acid generates a beneficial microenvironment for liver progenitor cell activation in acute liver failure.
Sai WangFrederik LinkStefan MunkerWenjing WangRilu FengRoman LiebeYujia LiYe YaoHui LiuChen ShaoMatthias P A EbertHui-Guo DingSteven DooleyHong-Lei WengShan-Shan WangPublished in: Hepatology communications (2024)
During ALF, RA secreted by activated HSCs promotes LPC activation, a prerequisite for subsequent LPC-mediated liver regeneration.