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Mutations in the DNA polymerase binding pathway affect the immune microenvironment of patients with small-cell lung cancer and enhance the efficacy of platinum-based chemotherapy.

Anqi LinWeiming MouLingxuan ZhuTao YangChaozheng ZhouJian ZhangPeng Luo
Published in: Cancer innovation (2023)
DNA polymerase binding pathway mutations can be used as prognostic markers for platinum-based chemotherapy in SCLC.
Keyphrases
  • small cell lung cancer
  • circulating tumor
  • cell free
  • single molecule
  • locally advanced
  • stem cells
  • structural basis
  • binding protein
  • squamous cell carcinoma
  • nucleic acid
  • chemotherapy induced
  • rectal cancer