Sialylated IgG-Fc: a novel biomarker of chronic inflammatory demyelinating polyneuropathy.

Anna Hiu Yi WongYuki FukamiMakoto SudoNorito KokubunShinsuke HamadaNobuhiro Yuki

Published in: Journal of neurology, neurosurgery, and psychiatry (2015)

Sialylation of IgG-Fc is reduced in CIDP. Its level correlated with clinical severity and increased after IVIG treatment. Sialylated as well as ratio of sialylated/agalactosylated IgG-Fc could be new measures to monitor the disease severity and treatment status in CIDP.

Keyphrases

oxidative stress
combination therapy
replacement therapy