Clinical and Analytical Performance of a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay.

Luca KoechlinJasper BoeddinghausPedro Lopez-AyalaCornelia ReberThomas NestelbergerKarin WildiCarlos C SpagnuoloIvo StrebelJonas GlaeserPaolo BimaLuca CrisantiLourdes Herraiz-RecuencoElisa DubachÒscar MiróF Javier Martin-SanchezDamian KaweckiDagmar I KellerMichael ChristAndreas BuserMaria Rubini GiménezGro Leite StørvoldMarianne Nordlund BroughtonTorbjørn OmlandMagnus N LyngbakkenHelge RøsjøChristian Muellernull null

Published in: Journal of the American College of Cardiology (2024)

The SPINCHIP hs-cTnI POC test has very high diagnostic accuracy. Its assay-specific 0/1-hour algorithm achieved very high sensitivity/negative predictive value and specificity/positive predictive value for rule-out/in MI. (Advantageous Predictors of Acute Coronary Syndromes Evaluation [APACE] Study [APACE]; NCT00470587).

Keyphrases

acute coronary syndrome
high throughput
blood pressure
machine learning
deep learning
antiplatelet therapy
single cell
mass spectrometry
atrial fibrillation