Differential expression of MAP3K7 and TROPONIN C proteins and related perturbations in renal amyloidosis.
Nimisha GuptaTahreem SaharDinesh KhullarS K JainSaima WajidPublished in: Expert review of proteomics (2020)
The results indicate that these proteomic signatures may be considered as potential molecular targets for RA diagnostics and therapeutics subject to validation on large sample size. Abbreviations: AβP= Amyloid-beta protein, Aβ=Amyloid-beta, AL= Light chain amyloidosis, AA= Amyloid A, ALECT2= LECT2 amyloidosis, APS= Ammonium persulfate CKD= Chronic Kidney Diseases, EBRT= external beam radiation therapy, ESRD= End-Stage Kidney Disease, Glis2= Gli-similar 2, JNK= c-Jun NH 2-terminal kinase, MAPK= Mitogen-Activated Protein Kinase, MM=Multiple Myeloma, PHD= Prolyl hydroxylase, RA = Renal Amyloidosis, SAA= Serum Amyloid A, SD= Standard Deviation, Sepp= Selenoprotein, SCC= Squamous cell carcinoma, SDS= Sodium dodecyl sulfate, TEMED = tetramethyl ethylenediamine, TGF-Beta-1=Transforming growth factor- Beta-1, Trx = Thioredoxin, TrxR= Thioredoxin reductase.
Keyphrases
- multiple myeloma
- transforming growth factor
- squamous cell carcinoma
- radiation therapy
- epithelial mesenchymal transition
- rheumatoid arthritis
- signaling pathway
- chronic kidney disease
- tyrosine kinase
- disease activity
- oxidative stress
- small molecule
- cell death
- protein kinase
- ankylosing spondylitis
- induced apoptosis
- gene expression
- systemic lupus erythematosus
- genome wide
- locally advanced
- interstitial lung disease
- risk assessment
- amino acid
- dna methylation
- cell proliferation
- protein protein
- idiopathic pulmonary fibrosis
- perovskite solar cells