Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germline variants of unknown significance (VUS) in BRCA1 and BRCA2 genes.

Anna Maria MilitelloGiulia OrsiAlessandro CavaliereMonica NigerAntonio AvalloneLisa SalvatoreGiampaolo TortoraIlario Giovanni RapposelliGuido GiordanoSilvia NoventaElisa GiommoniSilvia BozzarelliMarina MacchiniUmberto PerettiLetizia ProcaccioAlberto PucciniStefano CascinuCristina MontagnaMichele MilellaMichele Reni

Published in: Cancer chemotherapy and pharmacology (2023)

Pl-CT does not seem to be associated with a better outcome compared to AG chemotherapy in PDAC patients with BRCA 1/2 VUS.

Keyphrases

breast cancer risk
locally advanced
computed tomography
copy number
genome wide
image quality
contrast enhanced
gene expression
chemotherapy induced
radiation therapy
dual energy
highly efficient
positron emission tomography
oxidative stress
dna damage
transcription factor
pet ct