Translating biobehavioral research advances into improvements in health care-a "network of networks" approach to multimorbidity.

Biobehavioral research has made great advances in past decades, allowing researchers to paint an ever-improving picture of interactions between the central nervous system and the systems in the periphery of the body. This knowledge allows us, from a researcher's perspective, to better understand diseases and disease symptoms that are not explainable with a narrow view on organ-specific biomedical processes. However, what is lacking is the translation of this knowledge into clinical practice. In their commentary, Sturmberg et al pointed out these shortcomings and proposed a model connecting the different networks in the human body, and the importance of their connectedness, and drew conclusions for necessary changes in patient care. While doing so, Sturmberg et al also created the basis of what could be considered a new and all-encompassing stress model. This work therefore not only calls for changes in clinical practice but also provides a basis for further steps in biobehavioral research.