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Beneficial Effects of Oral Carbon Monoxide on Doxorubicin-Induced Cardiotoxicity.

Rodrigo W Alves de SouzaVanessa VoltarelliDavid GalloSidharth ShankarMichael S TiftMark YoungEdward GompertsAndrew GompertsLeo Edmond Otterbein
Published in: Journal of the American Heart Association (2024)
These findings strongly support using HBI-002 as a cardioprotective agent that maintains the therapeutic benefits of doxorubicin cancer treatment while mitigating cardiac damage.
Keyphrases
  • drug delivery
  • cancer therapy
  • high glucose
  • diabetic rats
  • oxidative stress
  • left ventricular
  • drug induced
  • endothelial cells
  • heart failure