Obesity has been long recognized as a risk factor for the development of heart failure, but recent evidence suggests obesity is more typically associated with heart failure with preserved ejection fraction as opposed to heart failure with reduced ejection fraction (HFrEF). Nevertheless, numerous studies have found that obesity modulates the presentation and progression of HFrEF and may contribute to the development of HFrEF in some patients. Although obesity has definite negative effects in HFrEF patients, the effects of intentional weight loss in HFrEF patients with obesity have been poorly studied.
Keyphrases
- weight loss
- heart failure
- insulin resistance
- metabolic syndrome
- high fat diet induced
- type diabetes
- end stage renal disease
- bariatric surgery
- weight gain
- roux en y gastric bypass
- ejection fraction
- newly diagnosed
- chronic kidney disease
- gastric bypass
- peritoneal dialysis
- adipose tissue
- atrial fibrillation
- left ventricular
- body mass index
- skeletal muscle
- glycemic control
- patient reported outcomes
- acute heart failure
- obese patients