Transferrin receptor 1 promotes hepatocellular carcinoma progression and metastasis by activating the mTOR signaling pathway.

Fu WangWei-Qi XuWan-Qin ZhangRu-Chen XuJia-Lei SunGuang-Cong ZhangZhi-Yong LiuZhuo-Ran QiLing DongShu-Qiang WengXi-Zhong ShenTao-Tao LiuYing FangJi-Min Zhu

Published in: Hepatology international (2023)

Our study indicates that TFRC exerts an oncogenic role in HCC and may become a promising therapeutic target to restrain HCC progression.

Keyphrases

signaling pathway
epithelial mesenchymal transition
transcription factor
induced apoptosis