Myeloid derived suppressor cells contribute to the malignant progression of oral squamous cell carcinoma.

Xin PangHua-Yang FanYa-Ling TangSha-Sha WangMing-Xin CaoHao-Fan WangLu-Ling DaiKe WangXiang-Hua YuJing-Biao WuYa-Jie TangXin-Hua Liang

Published in: PloS one (2020)

These indicated that the crosstalk between MDSCs and tumor cells facilitated the malignant progression of OSCC cells and the immune suppressive properties of MDSCs, which may provide new insights into tumor treatment on targeting tumor-associated immunosuppressive cells.

Keyphrases

induced apoptosis
cell cycle arrest
cell death
signaling pathway
pi k akt