Comparative anti-proliferative effects of potential HER2 inhibitors on a panel of breast cancer cell lines.

Hiba M ZalloumTuka AbuThiabTareq HameduhSara AlBayyariWaleed ZalloumBasha'er Abu-IrmailehMohammad S MubarakMalek A Zihlif

Published in: Breast cancer (Tokyo, Japan) (2019)

Our pharmacophore model resulted in a high potent ligand that shows high potency against HER2 positive breast cancer and relatively low toxicity towards the normal human cells.

Keyphrases

positive breast cancer
molecular dynamics
oxidative stress
molecular docking
young adults
childhood cancer