Targeting GPC2 on intraocular and CNS metastatic retinoblastomas with local and systemic delivery of CAR T-cells.
Guillem Pascual-PastoBrendan McIntyreAnna Maria GiudiceFatemeh AlikaramiAmanda MorrisseyStephanie MatlagaTed J HofmannVictor BurgueñoKyra HarveyDaniel MartinezAmish C ShahJessica B FosterJennifer PogorilerRalph C EagleAngel Montero CarcabosoCarol L ShieldsAnn-Marie LeaheyKristopher R BossePublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
GPC2-directed CAR T-cells are effective against intraocular and CNS metastatic retinoblastomas.