Acute dapagliflozin administration exerts cardioprotective effects in rats with cardiac ischemia/reperfusion injury.

Sarayut LahnwongSiripong PaleeNattayaporn ApaijaiSirawit SriwichaiinSasiwan KerdphooThidarat JaiwongkamSiriporn C ChattipakornSiriporn C Chattipakorn

Published in: Cardiovascular diabetology (2020)

Acute dapagliflozin administration during cardiac I/R injury exerted cardioprotective effects by attenuating cardiac infarct size, increasing LV function and reducing arrhythmias. These benefits indicate its potential clinical usefulness.

Keyphrases

liver failure
left ventricular
ischemia reperfusion injury
respiratory failure
aortic dissection
oxidative stress
intensive care unit
hepatitis b virus
congenital heart disease
acute coronary syndrome
coronary artery disease
mechanical ventilation
acute respiratory distress syndrome