The SPID-GBA study: Sex distribution, Penetrance, Incidence, and Dementia in GBA-PD.

Letizia Straniero Rosanna AsseltaSalvatore BonvegnaValeria RimoldiGiada MelistaccioGiulia Soldà Massimo Aureli Matteo Giovanni Della PortaUgo LuccaAlessio di FonzoAnna ZecchinelliGianni Pezzoli Roberto Cilia Stefano Duga

Published in: Neurology. Genetics (2020)

We report a large monocentric study on GBA-PD assessing mutation-specific data on the sex distribution, penetrance, incidence, and association with dementia of the 4 most frequent deleterious variants in GBA.

Keyphrases

mild cognitive impairment
risk factors
cognitive impairment
gene expression
big data
dna methylation
data analysis