Login / Signup

Combined use of Oxford Nanopore and Illumina sequencing yields insights into soybean structural variation biology.

Marc-André LemayJonas A SibbesenDavoud TorkamanehJérémie HamelRoger C LevesqueFrançois Belzile
Published in: BMC biology (2022)
We show that structural variants discovered using Oxford Nanopore data can be genotyped with high accuracy from Illumina data. Our results demonstrate that long-read and short-read sequencing technologies can be efficiently combined to enhance SV analysis in large populations, providing a reusable framework for their study in a wider range of samples and non-model species.
Keyphrases
  • single molecule
  • electronic health record
  • single cell
  • big data
  • solid state
  • copy number
  • genetic diversity
  • high throughput sequencing
  • machine learning
  • dna methylation
  • gene expression
  • genome wide