Sex differences in mitochondrial gene expression during viral myocarditis.

Damian Di FlorioDavid GorelovElizabeth McCabeDanielle BeetlerKatie ShapiroKatelyn BrunoIsha ChekuriAngita JainEmily WhelanGary SalomonSami KhatibNatalie Bonvie-HillPresley GiresiVarsini BalamuruganGabriel WeigelJessica FliessAshley DarakjianBrandy EdenfieldChristian KocsisChristopher McLeodLeslie CooperEtienne Audet-WalshMichael CoronadoJon SinDeLisa Fairweather

Published in: Research square (2023)

Master regulators of mitochondrial function were elevated in females with myocarditis compared to males and may promote sex differences in mitochondrial respiratory transcript expression during viral myocarditis resulting in less severe myocarditis in females following viral infection.

Keyphrases

gene expression
sars cov
oxidative stress
transcription factor
early onset
rna seq
respiratory tract