Delayed Hemolysis With Parenteral Artesunate.

Alfred Awuah Punit Jitendra ShahFarheen Tariq

Published in: Hospital pharmacy (2022)

Artesunate is an effective and first-line therapy option in patients with severe malaria caused by Plasmodium species. Among adverse effects of the drug is a phenomenon of delayed hemolysis. This usually occurs at least 7 days after initiation of therapy, and is characterized by reductions in hemoglobin and haptoglobin and an increase in lactate dehydrogenase. Here, we report an instance of delayed hemolysis in a patient probably attributed to parenteral artesunate therapy.

Keyphrases

red blood cell
stem cells
plasmodium falciparum
case report
early onset
emergency department
cell therapy
genetic diversity