Marked intestinal trans-differentiation by autoimmune gastritis along with ectopic pancreatic and pulmonary trans-differentiation.

Chihiro TakeuchiJunichi SatoNobutake YamamichiNatsuko Kageyama-YaharaAkiko SasakiTakemi AkahaneRika AokiShigemi NakajimaMasayoshi ItoMitsue YamamichiYu-Yu LiuNobuyuki SakumaYu TakahashiYoshiki SakaguchiYosuke TsujiKouhei SakuraiShuta TomidaKeiko NiimiToshikazu UshijimaMitsuhiro Fujishiro

Published in: Journal of gastroenterology (2023)

AIG induces diverse trans-differentiation in the gastric mucosa, characterized by the transactivation of genes specific to the small intestine, pancreas, and lung. Increased environmental pH owing to AIG may cause abnormal differentiation of the gastric mucosa.

Keyphrases

helicobacter pylori
pulmonary hypertension
genome wide
risk assessment
transcription factor
climate change
human health
drug induced
life cycle