Tissue-specific early and late activated lymphocytes immunophenotype in chronic rhinosinusitis with nasal polyps.
Soledad Lopez-EnriquezCristina Porras-GonzálezRamon Moreno-LunaFrancisca PalomaresJosé Luis Muñoz-BravoGonzalo AlbaConsuelo Santa-MaríaJuan Maza-SolanoDaniel Iván Martín-JiménezAntonio Pérez-PérezRafael Moreno-LunaVíctor Sánchez-MargaletSerafín Sánchez-GómezPublished in: International forum of allergy & rhinology (2024)
T-cell activation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is enriched by late cytotoxic T cells. The proportion of early and intermediate activated cytotoxic T cells decreases in nasal polyps of patients with CRSwNP. Our results identify late activated cytotoxic T cells as potential biomarkers or therapeutic targets for patients with CRSwNP.
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