A calcium message for Niemann-Pick type C.

Published in: The Journal of cell biology (2019)

Calcium is a ubiquitous secondary messenger that is critical for cellular function. In the highlighted article, Tiscione et al. (2019. J. Cell. Biol. https://doi.org/10.1083/jcb.201903018) describe a link between lysosomal cholesterol storage, calcium distribution alterations, and neuronal morphology in the neurodegenerative disorder Niemann-Pick type C.

Keyphrases

cell therapy
stem cells
mesenchymal stem cells
brain injury
bone marrow
blood brain barrier
subarachnoid hemorrhage
cerebral ischemia