Thyroid Stimulating Hormone Triggers Hepatic Mitochondrial Stress through Cyclophilin D Acetylation.

Xiaolei WangJinbao MaoXinli Zhou Qiu Li Ling Gao Jiajun Zhao

Published in: Oxidative medicine and cellular longevity (2020)

TSH stimulates hepatic CypD acetylation through the lncRNA-AK044604/SIRT1/SIRT3 signaling pathway, indicating an essential role for TSH in mitochondrial stress in the liver.

Keyphrases

oxidative stress
signaling pathway
ischemia reperfusion injury
induced apoptosis
histone deacetylase
stress induced
epithelial mesenchymal transition
long non coding rna