Inhibition of the bromodomain and extra-terminal family of epigenetic regulators as a promising therapeutic approach for gastric cancer.

Sun Kyoung KangHyun Joo BaeWoo Sun KwonTae Soo KimKyoo Hyun KimSejung ParkSeo Young YuJihyun HwangJuin ParkHyun Cheol ChungSun Young Rha

Published in: Cellular oncology (Dordrecht) (2021)

Collectively, our data suggest that iBET-151 is a potential therapeutic agent for GC, especially in combination with paclitaxel, and that WNT5B and IRS2 may predict iBET-151 sensitivity.

Keyphrases

dna methylation
electronic health record
cell proliferation
stem cells
gene expression
big data
transcription factor
artificial intelligence
high resolution
deep learning
simultaneous determination