Managing valvular pathology during LVAD implantation.
Michael J CarrSusan Ansley SmithMark S SlaughterSiddharth PahwaPublished in: Indian journal of thoracic and cardiovascular surgery (2023)
Since the time of their invention, implantable continuous flow left ventricular assist devices (LVADs) have improved the quality of life and extended survival for patients with advanced heart failure. The decision surgeons and their physician colleagues make with these patients to undergo implantation must come with full understanding of the immediate, short-term, and long-term implications of such a life-changing procedure. The presence of pathology regarding the aortic, mitral, and tricuspid valves introduces particularly complex problems for the surgical treatment strategy. Concomitant valve repair or replacement increases cardiopulmonary bypass and cross clamp times, and could potentially lead to worse outcomes in the perioperative setting. Following perioperative recovery, valvular pathology may worsen or arise de novo given the often drastic immediate physiologic changes in blood flow, septal function, and, over time, ventricular remodeling. Over the past two decades, there has been vast improvement in the device manufacturing, surgical techniques, and medical management surrounding LVAD implantation. Yet, addressing concomitant valvular pathology remains a complex question with no perfect solutions. This review aims to briefly describe the evolution of approach to valvular pathology in the LVAD patient and offer our opinion and treatment rationale.
Keyphrases
- aortic valve
- left ventricular
- heart failure
- aortic stenosis
- atrial fibrillation
- mitral valve
- blood flow
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- hypertrophic cardiomyopathy
- left atrial
- healthcare
- oral anticoagulants
- cardiac resynchronization therapy
- cardiac surgery
- patients undergoing
- newly diagnosed
- mental health
- emergency department
- acute myocardial infarction
- left ventricular assist device
- clinical trial
- case report
- type diabetes
- coronary artery disease
- minimally invasive
- catheter ablation
- combination therapy
- smoking cessation
- free survival
- percutaneous coronary intervention
- patient reported outcomes
- weight loss
- acute heart failure
- insulin resistance