Tumor Digital Masking Allows Precise Patient Triaging: A Study Based on Ki-67 Scoring in Gastrointestinal Stromal Tumors.
Piotr LewitowiczJaroslaw MatykiewiczMagdalena ChrapekDorota KozielAgata Horecka-LewitowiczMartyna Gluszek-OsuchIwona WawrzyckaStanisław GluszekPublished in: Scanning (2018)
Tumor digital masking is very promising solution for repeatable and objective labelling. Software adjustments of nuclear shape, outlines, size, etc. are helpful to omit other Ki-67-positive cells especially small lymphocytes. Our results pointed to Ki-67 as a good biomarker in GIST, but concurrently, we noted significant differences in used digital approaches which could lead to unequivocal results.