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Atomically precise silver clusterzymes protect mice from radiation damages.

Jiao GuoHaiyu YangYa LiuWei LiuRuiying ZhaoHe LiWei LongWenqing XuMeili GuoXiaodong Zhang
Published in: Journal of nanobiotechnology (2021)
In summary, atomically precise, ultrasmall and water soluble Ag14 clusterzymes with SOD-like activity were successfully developed and proved to be effective both in vitro and in vivo for radioprotection. Furthermore, with atomically precise molecular structure, Ag14 clusterzymes, on aspect of the catalytic and optical properties, may be improved by structure optimization on atom-scale level for other applications in disease diagnosis and treatment.
Keyphrases
  • water soluble
  • quantum dots
  • gold nanoparticles
  • highly efficient
  • molecular dynamics
  • visible light
  • high fat diet induced
  • type diabetes
  • amyotrophic lateral sclerosis
  • insulin resistance
  • skeletal muscle