Targeting the receptor tyrosine kinase MerTK shows therapeutic value in gastric adenocarcinoma.

Naita Maren WirsikMingyi ChenLiping HeUraz YasarJustus GaukelAlexander QuaasHenrik NienhüserElla LeugnerShuai YuanNikolai SchleussnerJin-On JungJadie Sue PlückerMartin SchneiderThomas Schmidt

Published in: Cancer medicine (2024)

Our findings demonstrate the potential value of MerTK as a prognostic biomarker for gastric adenocarcinoma. Targeting MerTK may become a new treatment option, especially for patients with advanced tumors, and may overcome resistance to established chemotherapies.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
squamous cell carcinoma
cancer therapy
locally advanced
radiation therapy
risk assessment
replacement therapy
rectal cancer
binding protein