In this review, the inherited conditions and reported genes of undetermined significance from case reports associated with SCAD are collected. A brief description of the encoded protein and the clinical features associated with pathologic genes is provided. Current data suggested that the diagnostic yield of genetic studies for patients with SCAD would be low and routine genetic screening of such patients with no clinical features indicative of associated disorders remains debatable. This review can be used as a guide for clinicians to recognize inherited syndromic and nonsyndromic disorders associated with SCAD.
Keyphrases
- genome wide
- coronary artery
- copy number
- pulmonary artery
- bioinformatics analysis
- case report
- neoadjuvant chemotherapy
- genome wide identification
- palliative care
- electronic health record
- gene expression
- big data
- case control
- transcription factor
- genome wide analysis
- radiation therapy
- binding protein
- amino acid
- pulmonary hypertension
- machine learning
- deep learning
- rectal cancer