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A noncanonical FLT3 gatekeeper mutation disrupts gilteritinib binding and confers resistance.

Sunil Kumar JoshiSetareh SharzehiJanét PittsenbargerDaniel BottomlyCristina E TognonShannon K McWeeneyBrian J DrukerElie Traer
Published in: American journal of hematology (2021)
Keyphrases
  • acute myeloid leukemia
  • tyrosine kinase
  • dna binding
  • binding protein
  • transcription factor