Visible Light-Induced Regioselective Cycloaddition of Benzoyl Azides and Alkenes To Yield Oxazolines.
Peter BellottiJulien BrocusFatima El OrfMohamed SelktiBurkhard KönigPhilippe BelmontEtienne BrachetPublished in: The Journal of organic chemistry (2019)
Visible light catalysis allows the regioselective synthesis of oxazolines in high yields. The mild photosensitized manifold leverages the intermolecular formation of oxazolines with a wide functional group tolerance on both benzoyl azides and alkenes partners. Mechanistic investigations suggest the sensitization of the azide moiety as the key activation step.