Identification of Prognostic Immune Genes in Bladder Urothelial Carcinoma.

Qi-Sheng SuYan SunZunni ZhangZheng YangYuling QiuXiaohong LiWuning Mo

Published in: BioMed research international (2020)

A transcription factor-immune gene regulatory network related to the prognosis of bladder urothelial carcinoma was established. EBF1, IRF4, SOX17, MEF2C, NFATC1, STAT1, ANXA6, SLIT2, and IGF1 were identified as hub genes in the network. The proportional hazards regression model constructed by 16 immune genes shows a good predictive ability for the prognosis of bladder urothelial carcinoma.

Keyphrases

bioinformatics analysis
transcription factor
genome wide identification
spinal cord injury
genome wide
urinary tract
cell proliferation
genome wide analysis
dendritic cells
immune response
gene expression
dna binding
pi k akt
growth hormone